GSTa2 Antikörper

Produktnummer ABIN7114646

Der Kaninchen Polyklonal Anti-GSTa2-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, GSTa2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GSTa2 Antikörper (ABIN7114646)

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTa2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-GSTa2 Antikörper

Verwendungszweck: GSTA2 antibody

Aufreinigung: Immunogen affinity purified

Reinheit: ≥95 % as determined by SDS-PAGE

Immunogen: glutathione S-transferase alpha 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu GSTa2

Target: GSTa2 (Glutathione S-Transferase alpha 2 (GSTa2))

Andere Bezeichnung: GSTA2

Hintergrund:

Synonyms: Glutathione S-transferase A2|GST HA subunit 2|GST class-alpha member 2|GST-gamma|GSTA2-2|GTH2|GSTA2|GST2

Background: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti- cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

Molekulargewicht: 25 kDa

Gen-ID: 2939

UniProt: P09210